Experimental mouth rinse with nano-HAp to be used at home for dental erosion treatment

Fernanda Signorelli Calazans, Marcelino José dos Anjos, Ramon Silva dos Santos, Rafael Pinto de Mendonça, Thárcila de Medeiros Jabor Ferreira, Gabriela Ribeiro Pereira, Joaquim Teixeira de Assis, Mauro Sayão de Miranda

Objective: The aim of this in vitro study was to evaluate — by X-ray fluorescence technique (XRF), surface Vickers microhardness (VM) and SEM — the effect of the following products in bovine enamel submitted to acidic challenges: nanoparticles of calcium hydroxyapatite (nano- HAp), associated or not with fluoride, casein phosphopeptide- amorphous calcium phosphate (CPP-ACP) associated or not with fluoride, sodium fluoride, and saliva. Methods: 58 bovine incisors were sectioned into fragments and randomly divided into 8 groups and 2 specimens for initial SEM images. All teeth were initially evaluated and over a 10-day experimental period, the enamel samples were subjected to erosive demineralization for 6 X 2 min per day. The samples received the corresponding treatments: professional pastes (nano-HAp; nano- HAp and fluoride; CPP-ACP; CPP-ACP and fluoride) and aqueous solutions (NaF; nano-HAp and nano-HAp + NaF). The samples were rinsed again with distilled water for 1 min and stored in artificial saliva. The time between cycles was 1.5 h. All specimens were evaluated again. Results/ Conclusions: All treatments carried out in groups of professionals pastes were considered effective on mineral deposition of tooth enamel surface subjected to erosive challenge cycle. The groups that received treatment with solutions were effective, matching the final results to the control group, considering VM and SEM, except for the sodium fluoride solution (0.05%). The nano-HAp solution associated with fluoride promoted full recovery in P and Ca count during cycling and had increased VM similar to all groups of professional pastes.

Keywords: Dental erosion. Nanohydroxyapatite. CPP-ACP. Fluoride.

How to cite: Calazans FS, Anjos MJ, Santos RS, Mendonça RP, Ferreira TMJ, Pereira GR, Assis JT, Miranda MS. Experimental mouth rinse with nano-HAp to be used at home for dental erosion treatment. J Clin Dent Res. 2018 May-Aug;15(2):62-80. DOI: https://doi.org/10.14436/2447-911x.15.2.062-080.oar

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